DESCRIPTION. FORFIVO XL (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Revision Bulletins are posted by the first of each month. Each Revision Bulletin includes the reason for the change, the complete Monograph or General Chapter, and the official publication in which the Revision Bulletin will be incorporated. Major Depressive Disorder. Bupropion hydrochloride extended-release tablets (XL) are indicated for the treatment of major depressive disorder (MDD), as defined by the Diagnostic and Statistical Manual (DSM). Learn about Mylan's portfolio of products by searching for a specific product name or view our full product list below. Contains Nonbinding Recommendations Draft Guidance on Bupropion Hydrochloride This draft guidance, once finalized, will represent the Food and Drug Administration's (FDA's) Save money on your Wellbutrin XL® Tablets prescription by switching to Teva's FDA-approved generic version, Bupropion Hydrochloride Extended-Release Tablets, USP (XL) DESCRIPTION. WELLBUTRIN XL® (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin reuptake inhibitor, or other known antidepressant agents. Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate and Amphetamine Sulfate tablet Companies are required under Section 506C of the Federal Food, Drug, and Cosmetic Act (FD&C Act) (as amended by the Food and Drug Administration Safety and Innovation Act) to notify FDA of a permanent discontinuance of certain drug products, six months in advance, or if that is not possible, as soon as practicable. Additional information regarding each drug, including labelling, is available by clicking on the products below.